Covid-19 Maternal Severe Risk Is Not Higher Than The Average Person

Recently, the team of Qiao Jie and Zhao Yangyu of Peking University Third Hospital published the latest research results online in the New England Journal of Medicine, and found that the risk of maternal infection after developing COVID-19 virus is not higher than the general population The clinical characteristics of maternal infection with influenza virus are similar. The researchers retrospectively analyzed the epidemiology and clinical characteristics, laboratory and imaging characteristics, treatment and prognosis of pregnant women in 50 COVID-19 diagnosis and treatment designated hospitals in Wuhan from December 8, 2019 to March 20, 2020. And other data. This is a descriptive study of the largest sample size of COVID-19 infection in pregnant women in China. The results showed that there were 118 maternal infections in Wuhan during this period, accounting for 0.24% of COVID-19 patients in Wuhan during the same period. The median age of infected pregnant women was 31 years old, 52% of patients were primiparas, and 64% of patients were infected in the third trimester. The most common symptoms are fever (75%) and cough (73%). Lymphopenia occurred in 44% of patients, and 79% of patients had bilateral lung involvement on CT examination. During the study period, 68 pregnant women gave birth, giving birth to 70 newborns (including 2 twins), accounting for 0.56% of the births in Wuhan during the same period. There were 14 premature births in newborns, accounting for 21%, of which 8 cases were iatrogenic preterm births. There are no reports of neonatal asphyxia or death. Nucleic acid tests were performed on 8 neonatal pharyngeal swabs and 3 breast milk samples, all of which were negative. Among all infected pregnant women, 109 were mild and 9 were severe, accounting for 8%. Six patients who were admitted to the hospital with mild disease gradually developed into severe disease after delivery, and one patient who was admitted to the hospital was further aggravated after delivery and received noninvasive mechanical ventilation. As of March 20, there were no reports of maternal deaths. According to the available data, the research team believes that the aggravation of pregnant women after delivery may be related to the pathophysiological changes that occur after delivery (such as increased circulating blood volume).